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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIAM1 All Species: 18.18
Human Site: T1223 Identified Species: 66.67
UniProt: Q13009 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13009 NP_003244.2 1591 177508 T1223 H L D V A I K T M N K V A S H
Chimpanzee Pan troglodytes XP_001162796 1591 177528 T1223 H L D V A I K T M N K V A S H
Rhesus Macaque Macaca mulatta XP_001098107 1591 177452 T1223 H L D V A I K T M N K V A S H
Dog Lupus familis XP_544855 1591 177339 T1223 H L D V A I K T M N K V A S H
Cat Felis silvestris
Mouse Mus musculus Q60610 1591 177515 T1223 H L D V A I K T M N K V A S H
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91620 2061 229913 G1608 H L C E A L K G M E K V A E H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788791 1150 129570 N799 D D L V K Y E N M T W L N C H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.4 95.7 N.A. 95.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 27.5 N.A. N.A. 25.4
Protein Similarity: 100 99.8 99.6 97.8 N.A. 97.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 42.9 N.A. N.A. 40.7
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 60 N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 66.6 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 86 0 0 0 0 0 0 0 86 0 0 % A
% Cys: 0 0 15 0 0 0 0 0 0 0 0 0 0 15 0 % C
% Asp: 15 15 72 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 15 0 0 15 0 0 15 0 0 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % G
% His: 86 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % H
% Ile: 0 0 0 0 0 72 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 15 0 86 0 0 0 86 0 0 0 0 % K
% Leu: 0 86 15 0 0 15 0 0 0 0 0 15 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 15 0 72 0 0 15 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 72 0 % S
% Thr: 0 0 0 0 0 0 0 72 0 15 0 0 0 0 0 % T
% Val: 0 0 0 86 0 0 0 0 0 0 0 86 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % W
% Tyr: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _